Rugrats is a popular American animated television series that aired from 1991 to 2004. The show revolves around the adventures of a group of toddlers, including Tommy, Chuckie, Phil, Lil, and Angelica, as they navigate their world of imagination and discovery. The series was created by Arlene Klasky, Gabor Csupo, and Paul Germain and produced by Nickelodeon Animation Studio.

China, IL is an American adult animated television series created by Brad Neely for Cartoon Network's late-night programming block, Adult Swim. The series takes place in the fictional town of China, Illinois, and follows the lives of the faculty members of the University of China, Illinois, which is commonly referred to as "the worst college in America." The show is known for its absurd humor, pop culture references, and unique animation style.

A spin-off from Fox's monster hit "Family Guy," "The Cleveland Show" easily could inspire serious questions about whether or not three middle-aged white men ought to attempt writing comedy about African-Americans. Somehow, though, Seth MacFarlane, Mike Henry, and Richard Appel have attracted a devoted multi-racial, multi-cultural audience for Cleveland and his family by making their points gently and with genuine humor. Consistent with his approach to "Family Guy," MacFarlane reserves most of his animus for middle-aged white suburban guys a lot like himself. Cleveland and his family have moved back to his home town, Stoolbend, Virginia, where he lives with Junior, his high school crush, and her two children. The majority of Cleveland's funniest lines derive more from his cluelessness than his color, and the majority of the ethnic humor derives from the creators' brilliant satire of racial attitudes among unenlightened southern white people. Among MacFarlane's only-slightly-exaggerated redneck characters, Lester does the majority of the comic work, languishing on his Confederate flag folding chair and cleaning his beloved guns. In general, the racial humor remains tame if not always politically correct, and "The Cleveland Show" gets the vast majority of its big laughs from allusions to pop culture.

Sealab 2021 was an American animated television series that aired on Adult Swim from 2000 to 2005. The show was a parody of the 1970s animated series Sealab 2020, which was about a research facility on the ocean floor. Sealab 2021 reuses the original footage from Sealab 2020 and combines it with new animation and comedic voiceovers to create a completely different show.

Either the CIA is just not that cool and relevant anymore, or Seth Macfarlane and associates are still mining the mother lode of 1970s humour as they develop episodes of "American Dad!" for Sunday nights on Fox. Television historians claim animated series have replaced sit-coms as television's principal source of informed social commentary; and "The Simpsons" have replaced "All in the Family" as the nation's premier satire, the weekly litmus test of American values and expectations. "American Dad!" shows little sign of aspiring to that lofty standing. Most episodes set the standard simply at "amusing." CIA agent and uber-patriot Stan Smith, the "American Dad!" anchors a predictably diverse, dysfunctional just-beyond-the-beltway family. Francine, his wife, appears to atone for her wild youth by remaining vacant, mostly boring in contemporary life. Hayley, Stan's college-aged radical daughter, naturally acts-out all the standard forms of late adolescent rebellion and family insurgency. And Steve, not surprisingly, enters puberty eager to live-up to Dad's expectations but congenitally incapable of coming even close. Holding its own in Fox's Sunday night animated line-up, "American Dad!" has improved in its several seasons on the air. Translation: "American Dad!" has evolved from "mediocre" to "not bad" as it has outgrown its abject dependence on cliches and stereotypes, freshened its subject matter and treatment, and drawn sharper edges on its characters. Still, the premises for "American Dad!" showed promise in 1973; in the new millennium, they seem a little tired.

Space Ghost Coast to Coast is an American animated television series that originally aired from 1994 to 2004. The show featured the character Space Ghost, a 1960s Hanna-Barbera cartoon superhero who, in this series, was repurposed as a talk show host. The show was unique in that it was a combination of traditional animation and live-action interviews.