Mr. & Mrs. Smith is a 2024 spy drama series created by Donald Glover and Francesca Sloane for Amazon Prime Video, reimagining the 2005 Brad Pitt and Angelina Jolie film as something tonally, thematically, and structurally different. Using the premise of two strangers assigned to pose as a married couple of spies, Glover and Sloane build a show that is fundamentally about the psychology of intimacy, the performance of partnership, and the impossibility of separating the professional from the personal. Glover stars as John and Maya Erskine as Jane: two candidates selected by an anonymous organization to live as husband and wife while carrying out assignments of escalating danger and moral opacity.

The series is structured as a season-long examination of what happens when the fiction of a relationship becomes the relationship itself. John and Jane begin with nothing in common except their cover story, and the show tracks how that shared pretense — sustained under life-threatening pressure — generates something neither can easily categorize or abandon. Each episode is built around a mission that illuminates something about the couple's growing entanglement, with guest appearances by Ron Perlman, Paul Dano, Parker Posey, John Turturro, and Wagner Moura in roles designed to put pressure on the assignment in different ways.

Mr. & Mrs. Smith became one of Amazon's most-talked-about original series of 2024, praised for Glover and Erskine's extraordinary chemistry, Sloane's characteristically dense and emotionally precise dialogue, and the show's resistance to conventional spy genre expectations. Critics consistently noted that it functions less as an action series than as an intimate relationship drama that happens to involve firearms and tradecraft. It streams exclusively on Prime Video.