Although the producers of "Family Guy" claim that it represents a "dysfunctional" family, millions of American viewers say it looks perfectly representative of most of the families in their neighborhood. Part of the "animation domination" line-up on Fox Network, "Family Guy" dramatizes the everyday dramas in the lives of Peter and Lois Griffin, their children Meg, Chris, and Stewie, and their dog Brian. Like all Seth MacFarlane productions, "Family Guy" depends on scathing satire of American popular culture for most of its humor, stretching the "plausible impossible" to make the baby and the dog by far the smartest and most perceptive among the members of the family. The Griffins have garnered three Emmys and three Annies for MacFarlane and company, and they have earned one Golden Reel Award. In 2009, "Family Guy" earned an Emmy nomination for Outstanding Comedy Series"”the first time since "The Flintstones" were nominated in 1962 that an animated series had numbered among the nominees.

Harley Quinn is an adult animated TV series that premiered on DC Universe in 2019. It follows the adventures of Harley Quinn, a former psychiatrist who breaks up with the Joker and sets out to become a supervillain in her own right. The series was created by Justin Halpern, Patrick Schumacker, and Dean Lorey.

Clarence is an American animated television series that aired on Cartoon Network from 2014 to 2018. The show follows the life of a young boy named Clarence and his friends as they navigate childhood and their daily adventures. The series was created by Skyler Page and produced by Cartoon Network Studios.

In their more than twenty years on Fox Network, the Simpsons have become not only a staple in the primetime line-up but also American cultural icons. Created by Matt Groening with early help from comedy genius James L. Brooks, "The Simpsons" brilliantly but brutally satirize working-class American life. Homer personifies the character of the average "working stiff," oblivious to the myriad ways his job and family abuse and exploit him. Marge, Homer's wife, captures the plight of the long-suffering housewife, imprisoned by but also devoted to her family. Precocious pre-teen Bart embodies every aggressive, rebellious, marginally criminal urge in adolescent American boys"”James Dean on a skateboard. Lisa, Bart's sister, represents every family's precious little princess; and Maggie is just "the baby." "The Simpsons" TV show owns a privileged place in American television history: In 2009, the simply but cleverly animated series surpassed "Gunsmoke" and "Law and Order," becoming the longest-running primetime series. Along the way to the record, "The Simpsons" became America's longest-running animated program and its longest-running sitcom. Even more impressively, "The Simpsons" earned a star on the Hollywood Walk of Fame, and Time magazine called it the twentieth century's best television series.

Curious George is a TV series based on the popular children's book character of the same name. The show was first aired in 2006 and has since become a favorite among young viewers. The series follows the adventures of a mischievous and curious monkey named George, who lives with his friend, The Man with the Yellow Hat, in a big city.

"12 oz. Mouse" is an American animated TV show that first aired in 2005. It was created by Matt Maiellaro, who also worked on "Aqua Teen Hunger Force." The show follows the adventures of a strange, alcoholic mouse named Fitz who often finds himself in bizarre situations. The animation style is intentionally crude and surreal, and the show often features strange, nonsensical humor.