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Love & Other Drugs pairs pharmaceutical salesman Jamie Randall with Maggie Murdock, a fiercely independent woman living with early-onset Parkinson’s disease. Their initially casual relationship develops as both confront the limits of Jamie’s charm and Maggie’s determination to avoid dependence on another person. Jake Gyllenhaal and Anne Hathaway lead the cast, with Oliver Platt, Hank Azaria, Josh Gad and Gabriel Macht in supporting roles.
Edward Zwick directed and co-wrote the romantic comedy with Charles Randolph and Marshall Herskovitz, adapting Jamie Reidy’s nonfiction book Hard Sell: The Evolution of a Viagra Salesman. The film opened in Los Angeles and New York on November 24, 2010. AFI records a 112-minute runtime and an R rating, matching the current U.S. Google Play listing.
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